Kinesin motors drive the long-distance Peizo Ignitor anterograde transport of cellular components along microtubule tracks.Kinesin-dependent transport plays a critical role in neurogenesis and neuronal function due to the large distance separating the soma and nerve terminal.The fate of kinesin motors after delivery of their cargoes is unknown but

The hydraulic pipeline is subject to the aero-engine base excitation and the pump fluid pulsation which can always damage the pipeline through overload to fatigue.So, the health monitoring technique of hydraulic pipeline is essential for the maintenance of the aero-engine.In this article, the Kalman filter combined with fiber Bragg grating method i

Azoles are the main antifungal agents employed in clinical practice to treat invasive candidiasis.Nonetheless, their efficacy is limited by fungal resistance mechanisms, mainly the overexpression of efflux pumps.Consequently, candidiasis has a worrisome death rate of 75%.One potential strategy to overcome efflux-mediated resistance is to inhibit th

Abstract Introduction Pain is one of the most frequently reported symptoms in hemodialyzed (HD) patients, with prevalence rates between 33% and 82%.Risk factors for chronic pain in HD patients are older age, long-lasting dialysis history, several concomitant diseases, malnutrition, and others.However, chronic pain assessment in HD patients is rarel

Purpose.To identify the demographic features of patients aged 65 years or older admitted with 2 episodes of fragility hip fractures.Methods.From July 2003 to December 2004 inclusive, 50 consecutive elderly patients underwent surgery for a second episode of hip fracture.Patients in a very poor physical condition and therefore unfit for surgery were